Publications

Key Publications

Nature, 2024
Coordinated inheritance of extrachromosomal DNAs in cancer cells
Hung KL*, Jones MG*, Wong ITL*, Curtis EJ*, Lange JT, He BJ, Luebeck J, Schmargon R, Scanu E, Brückner L, Yan X, Li R, Gnanasekar A, González RC, Belk JA, Liu Z, Melillo B, Bafna V, Dörr JR, Werner B, Huang W, Cravatt BF, Henssen AG, Mischel PS, Chang HY (*co-first authorship)

Nature Genetics, 2022
Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH
Hung KL, Luebeck J, Dehkordi SR, Colón CI, Li R, Wong ITL, Coruh C, Dharanipragada P, Lomeli SH, Weiser NE, Moriceau G, Zhang X, Bailey C, Houlahan KE, Yang W, Chamorro R, Swanton C, Curtis C, Jamal-Hanjani M, Henssen AG, Law J, Greenleaf WJ, Lo RS, Mischel PS, Bafna V, Chang HY

Nature Structural & Molecular Biology, 2022
Gene regulation on extrachromosomal DNA
Hung KL, Mischel PS, Chang HY

Nature, 2021
ecDNA hubs drive cooperative intermolecular oncogene expression
Hung KL*, Yost KE*, Xie L*, Shi Q, Helmsauer K, Luebeck J, Schöpflin R, Lange JT, Chamorro R, Weiser NE, Chen C, Valieva ME, Wong ITL, Wu S, Dehkordi SR, Duffy CV, Kraft K, Tang J, Belk JA, Rose JC, Corces MR, Granja JM, Li R, Rajkumar U, Friedlein J, Bagchi A, Satpathy AT, Tjian R, Mundlos S, Bafna V, Henssen AG, Mischel PS, Liu Z, Chang HY (*co-first authorship)

Molecular Therapy, 2018
Engineering protein-secreting plasma cells by homology-directed repair in primary human B cells
Hung KL, Meitlis I, Hale M, Chen C, Singh S, Jackson SW, Miao CH, Khan IF, Rawlings DJ, James RG

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